Felbamate (hydrate)_化工百科

中文名	Felbamate (hydrate)
英文名	Felbamate (hydrate)
别名	非尔氨酯水合物化合物 T22778
英文别名	FelbaMate (hydrate) Felbamate (hydrate)
CAS	1177501-39-1
化学式	C11H16N2O5
分子量	256.26
溶解度	10毫米DMSO
存储条件	-20℃
体外研究	Felbamate hydrate (W-554 hydrate) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy. Felbamate (W-554) has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptor of relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain.

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产品名: Felbamate hydrate 去供应商网站查看询盘
CAS: 1177501-39-1
产地: 上海
规格: F884211
价格: 50mg-2118,10mg-648
库存: 15天内发货
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上海源叶生物科技有限公司

产品名: Felbamate (hydrate) 去供应商网站查看询盘
CAS: 1177501-39-1
产地: 上海
规格: 98%
价格: 10mg 670,50mg 2190
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